Table 2.
Results of the univariate analyses of the risk factors of anastomotic leakage after colonic anastomosis.
| Risk factor | Anastomotic leak (n = 50) | No anastomotic leak (n = 1805) | p value |
|---|---|---|---|
| Mean age (SD) | 68.8 (14.9) | 64.9 (14.4) | 0.028 |
| Male gender | n = 33 | n = 876 | 0.021 |
| Median ASA score (Range) | 2 (1–4) | 2 (1–5) | 0.156 |
| Cardiac comorbidities | n = 28 | n = 810 | 0.322 |
| Vascular comorbidities | n = 5 | n = 174 | 1.000 |
| Diabetes | n = 10 | n = 153 | 0.022 |
| Pulmonary comorbidities | n = 9 | n = 224 | 0.396 |
| Tobacco abuse | n = 7 | n = 269 | 0.437 |
| Obesity | n = 28 | n = 938 | 1.000 |
| Dementia | n = 2 | n = 21 | 0.142 |
| Immunosuppressive drugs | n = 7 | n = 77 | 0.010 |
| Nonsteroidal anti-inflammatory drugs | n = 7 | n = 245 | 1.000 |
| Presence of cancer | n = 16 | n = 532 | 1.000 |
| Presence of peritonitis | n = 5 | n = 172 | 1.000 |
| Large bowel obstruction | n = 3 | n = 101 | 1.000 |
| Liver cirrhosis or severe fibrosis | n = 3 | n = 21 | 0.024 |
| Mean (SD) white blood cell count (1/10E9) | 8.5 (3.8) | 8.2 (4.0) | 0.300 |
| Mean (SD) haemoglobin level | 12.7 (2.4) | 13.3 (2.0) | 0.084 |
| Mean (SD) sodium level | 138.9 (4.2) | 140.0 (3.1) | 0.471 |
| Mean (SD) potassium level | 4.1 (0.5) | 4.1 (1.1) | 0.757 |
| Mean (SD) creatinine level | 88.4 (48) | 79.6 (43.6) | 0.131 |
| Mean (SD) albumin level | 37.6 (4.8) | 40.2 (5.7) | <0.001 |
SD: standard deviation; ASA: American Society of Anesthesiologists.