Table 3.
Univariate and multivariate analysis to predict pathological subtypes.
| Variable | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p value | OR | 95% CI | p value | |
| Age >60 years | 4.994 | 2.005–12.438 | 0.001∗ | 2.167 | 0.547–8.593 | 0.271 |
| Sex: male | 0.577 | 0.244–1.362 | 0.209 | — | — | — |
| Smoking status: current | 1.625 | 0.595–4.436 | 0.343 | — | — | — |
| Pure solid nodule on radiology | 36.561 | 4.972–268.878 | <0.001∗ | 12.681 | 1.562–102.972 | 0.017∗ |
| Serum CEA level >5 ng/mL | 6.129 | 1.270–29.583 | 0.024∗ | 1.143 | 0.117–11.131 | 0.908 |
| Serum miR-183 level >1.0 (2−ΔΔCt) | 2.006 | 0.853–4.716 | 0.110 | — | — | — |
| Tumour size >21 to ≤30 mm | 21.981 | 6.988–69.142 | <0.001∗ | 9.609 | 2.882–32.038 | <0.001∗ |
∗Statistically significant p value; —, not included in the multivariate analysis
OR, odds ratio; CEA, carcinoembryonic antigen; CI, confidence interval.