Table 3. . Multiple linear regression model evaluating the effects of IL1A rs1800587 on chronic pain in sickle cell disease .
| Model | B (95% CI)† | p-value | R2 | Adj. R2‡ |
|---|---|---|---|---|
| Additive |
3.85 (0.15–7.56) |
0.042 |
0.11 |
0.03 |
| Dominant |
5.66 (-1.26–12.58) |
0.108 |
0.10 |
0.02 |
| Recessive | 4.62 (-0.77–10.02) | 0.092 | 0.10 | 0.02 |
The major allele is the reference genotype in the analyses. Regression models are adjusted for age, sex, ethnicity and sickle cell type.
†Unstandardized regression coefficient and 95% confidence interval.
‡Adjusted R-square for six predictors (SNP, age, sex, ethnicity and sickle cell type).