FIG. 5.
HBe-positive and HBe-negative Hmy2.CIR proliferation in coculture systems with HBe-positive or HBe-negative U937. GV166-Hmy2.CIR and HBe-Hmy2.CIR were cocultured with GV166-U937 or HBe-U937 for indicated times. After that, proliferation of GV166-Hmy2.CIR and HBe-Hmy2.CIR was detected using Cell Counting Kit-8. Absorbance at 450 nm of each group was used to reflect cell proliferation. It showed that coculture with GV166-U937 or HBe-U937 did not influence GV166-Hmy2.CIR and HBe-Hmy2.CIR proliferation; however, HBe-Hmy2.CIR proliferation was significantly increased compared with GV166-Hmy2.CIR, whether cocultured with GV166-U937 or HBe-U937.