Table 6.

Change Point Thresholds from Baseline Constant Risk to Dose-Response Relation Between CHII and Risk of Impairment

Outcome measure	Clinical domain	Threshold*mean CHII for dose-response	95% CI
Behavioral Regulation Index of the BRIEF-A	Behavior	2216	1537-8120
Metacognition Index of the BRIEF-A	Metacognition	2393	1571-6682
Global Executive Composite of the BRIEF-A	Executive Function	1850	1523-2011
Center for Epidemiologic Studies Depression Scale	Depression	1801	1514-2010
Apathy Evaluation Scale	Apathy	2160	1536-5754
Brief Test of Adult Cognition by Telephone	Cognition	7251	1754-9788

^*The Mean and 95% CI from 30,000 Markov Chain Monte Carlo simulations. Change-point thresholds represent the mean number of impacts above which there is a predictive dose-response relationship between head impacts and clinically meaningful measures of impairment.

BRIEF-A, Behavior Rating Inventory of Executive Function – Adult Version.