Figure 7.

THA ameliorated space learning ability in the APP/PS1 transgenic mice. The MWM test was used to evaluate the effect of THA on the space learning ability of the AD model mice. (A) In training trials, the escape latencies to find the platform were measured to evaluate the memory ability of the mice (two-way ANOVA, Bonferroni's post hoc test. n=10. ^##P<0.01 compared with T-V). (B) Statistical analysis of (A) in for nine days of latency (t test. n=10. ^#P<0.05, ^##P<0.01 compared with T-V). NT-V, non-transgenic vehicle group; T-V, transgenic AD model vehicle group; T-THA, transgenic AD model with THA administration (300 mg·kg⁻¹·d⁻¹) group. Values are the mean±SEM.