Table 3.
Hazard ratios for the risk of graft loss and death in early steroid withdrawal versus continued steroid (reference) stratified by modifying variables and time periods
Outcome | Cytolytic Inductiona | Tacrolimusa | MMF/MPAa | Delayed Graft Functiona | ||||
---|---|---|---|---|---|---|---|---|
Yes | No | Yes | No | Yes | No | Yes | No | |
Graft loss (95% CI) | 0.90 (0.83 to 0.97) | 1.12 (1.02 to 1.24) | 0.92 (0.86 to 0.99) | 1.20 (1.05 to 1.36) | 0.93 (0.86 to 0.99) | 1.15 (1.01 to 1.30) | 1.19 (1.06 to 1.33) | 0.91 (0.85 to 0.98) |
Death (95% CI) | 0.80 (0.71 to 0.89) | 1.11 (0.97 to 1.26) | 0.83 (0.76 to 0.92) | 1.22 (1.03 to 1.44) | 0.81 (0.73 to 0.89) | 1.26 (1.06 to 1.48) | 1.05 (0.91 to 1.22) | 0.86 (0.78 to 0.95) |
MMF, mycophenolate mofetil; MPA, mycophenolic acid; 95% CI, 95% confidence interval.
P<0.05 for interaction between variable and early steroid withdrawal in Cox regression models.