Table 1.
Clinicopathologic characteristics of the 78 cases of culture positive staphylococcal infection–associated GN from 2004 to 2016 at the Ohio State University Medical Center
| Clinicopathologic Features | n | % |
|---|---|---|
| Age, yr | 55±12.1 (21–91) | |
| Ethnicity | ||
| White | 74 | 95 |
| Black | 3 | 3.8 |
| Asian | 1 | 1.2 |
| Sex | ||
| Men | 61 | 78 |
| Women | 17 | 22 |
| Diabetes mellitus | 32 | 41 |
| ANCA positive | 9 of 41 | 22 |
| Hepatitis C positive | 22 | 28 |
| Staphylococcal strain | ||
| MRSA | 42 | 59 |
| MSSA | 17 | 27 |
| MRSE | 3 | 1.20 |
| MSSE | 2 | 1.20 |
| Staph strain unknown | 7 | 11 |
| Mixed bacterial infection | 7 | 9 |
| Blood culture positive | 39 | 50 |
| Local wound culture positive | 43 | 55 |
| Both cultures positive | 4 | 5 |
| Low C3 | 19 of 64 | 30 |
| Low C4 | 9 of 64 | 14 |
| Both C3 and C4 low | 9 of 64 | 14 |
| Purpuric lower extremity skin rash | 16 | 20.5 |
| Nephrotic range proteinuria | 35 of 73 | 48 |
| Type and site of infection | ||
| Endocarditis | 18 | 21 |
| Bacteremia | 10 | 14 |
| Osteomyelitis, arthritis | 17 | 22 |
| Leg ulcers, cellulitis | 17 | 22 |
| Pneumonia | 6 | 8 |
| Others | 10 | 13 |
| Infected abdominal mesh | 1 | 1 |
| Post-surgical site infection | 1 | 1 |
| Visceral abscess | 6 | 8 |
| Urinary tract infection | 2 | 3 |
Patient age is shown as mean ± SEM (range). MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive Staphylococcus aureus; MRSE, methicillin-resistant Staphylococcus epidermidis; MSSE, methicillin-sensitive Staphylococcus epidermidis.