Table 4.
SAGN biopsies with trace or negative immunofluorescence staining for immunoreactants IgA, C3, IgG, or all three (pauci-immune pattern)
| SAGN Biopsies | Endocarditis (n=18) | Bacteremia of Unknown Source (n=10) | Osteomyelitis, Septic Arthritis (n=17) | Infected Skin Ulcers (n=17) | Pneumonia (n=6) | Others (n=10) | Total (n=78), n (%) |
|---|---|---|---|---|---|---|---|
| Trace or negative IgA | 6 | 3 | 4 | 3 | 2 | 2 | 20 (25) |
| Trace or negative C3 | 1 | 1 | 4 | 3 | 0 | 2 | 11 (14) |
| Trace or negative IgG | 10 | 3 | 11 | 10 | 3 | 9 | 46 (59) |
| “Pauci-immune pattern” (concomitantly trace or negative IgA, IgG, and C3, and few deposits on EM) | 1 | 1 | 4 | 2 | 0 | 2 | 10 (13) |
| Pauci-immune pattern and crescents | 1 | 0 | 2 | 0 | 0 | 3 | 6 of 10 (60) |
SAGN, Staphylococcus infection–associated GN; EM, electron microscopic examination.