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. 2017 Jan 5;35(2):248–254. doi: 10.1016/j.vaccine.2016.11.085

Table 2.

Group mean microscopic lesions and presence and amount of PCV2 antigen at 21 days post PCV2 challenge.

Group Lymphoid tissues
Lungs
Overall lymphoid depletion scorea PCV2 antigen in lymph nodesb Interstitial pneumoniac PCV2 antigen in lung tissuesb
NEG 0.1 ± 0.1A,d 0/10 (0.0 ± 0.0)A 0.4 ± 0.2A 0/10 (0.0 ± 0.0)
VAC 0.3 ± 0.2A,B 0/9 (0.0 ± 0.0)A 0.6 ± 0.2A,B 0/9 (0.0 ± 0.0)
VAC + CHAL 1.6 ± 0.7B 1/9 (0.1 ± 0.1)A 0.7 ± 0.3A,B 1/9 (0.1 ± 0.1)
CHAL 2.5 ± 0.7B 6/10 (0.9 ± 0.3)B 1.4 ± 0.3B 4/10 (0.1 ± 0.1)
a

Overall lymphoid depletion score ranging from 0 = normal to 9 = severe.

b

Determined by immunohistochemistry ranging from 0 = absent to 3 = abundant antigen.

c

Interstitial pneumonia score ranging from 0 = normal to 6 = severe.

d

Data presented as group mean ± SEM or as prevalence (group mean ± SEM). Groups connected by different superscripts within a column have significantly (P < 0.05) different group means.