Skip to main content
. Author manuscript; available in PMC: 2017 Jan 9.
Published in final edited form as: Brain Struct Funct. 2014 May 31;220(4):2415–2422. doi: 10.1007/s00429-014-0794-9

Fig. 2.

Fig. 2

Estradiol-mediated dendritic spine plasticity in the nucleus accumbens core and hippocampal CA1 depends on group I mGluRs. a Estradiol decreased dendritic spine density of medium spiny neurons in the nucleus accumbens core and this effect was attenuated by pretreatement with JNJ. b Neither estradiol nor JNJ had a significant effect on medium spiny neurons of the nucleus accumbens shell. c Estradiol increased dendritic spine density in hippocampal CA1 pyramidal neurons and pretreatment with JNJ blocked this effect. The number inside of each bar represents the number of animals per treatment condition. Grey bars are significantly different than white bars p< 0.05. d-f Cumulative probability distribution plots of dendritic spine density within treatment groups for nucleus accumbens core (d), nucleus accumbens shell (e), and CA1 region of the hippocampus (f)