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. Author manuscript; available in PMC: 2017 Jan 9.
Published in final edited form as: Hum Immunol. 2013 Jul 19;74(11):1486–1490. doi: 10.1016/j.humimm.2013.07.001

Table 1.

Organ Author Phenotype (Hyper Acute Rejection)/AR/Chronic Allograft Injury Study Size nHLA antibody (nHLA-Ab) References
Bialic et al chronic hemodialysis (pre-txp) 48 tubulin beta chain, vimentin, lamin-B1, and Rho GDP-dissociation inhibitor 2 [23]
Kidney Sutherland et al Acute Rejection 15 Protein Kinase Cζ [8]
Li et al Chronic Allograft Injury 33 Angiotensinogen (AGT) and Speedy homologue A (SPDYA) [14]
Li et al Acute Rejection 15 MICA [7]
Li et al Post-transplant Ab response 18 IgG's against 5,056 unique protein targets [10]
Butte et al ESRD 95 angiotensinogen and PRKRIP1
Sigdel et al Chronic Allograft Injury 98 MIG (CXCL9), ITAC (CXCL11), IFN-γ, glial-derived neurotrophic factor [13]
Chaudhuri et al Acute Rejection 124 MICA [36]
Dragun et al Refractory vascular rejection (AR) 33 Angiotensin II type 1 receptor antibody [33]
Dinavahi et al Chronic Allograft Injury 39 peroxisomal-trans-2-enoyl-coA-reductase [47]
Zou et al Acute Rejection 1910 MICA [35]
Narayan et al Acute Rejection 1 [34]
Jackson et al Acute Rejection 60 anti-endothelial cell antibodies (AECAs) [30]
Breimer et al Rejection 147 [32]
Sun et al Acute Rejection 226 [49]
Heart Ismail et al Acute Rejection 60 [50]
Fredrich et al cardiac allograft vasculopathy (CAV) 80 [31]
Acevedo et al Cardiac allograft vasculopathy (CAV) 48 anti-hnRNP-K antibodies [40]
Lung Smith et al Hyperacute rejection, Acute rejection 616 IgM Abs to nHLAs [15]
Otten et al Bronchiolitis obliterans syndrome (BOS) 11 PSMC4, F3, LOC284058, PLUNC, ZNF33A, XP_931864 [51]
Jaramillo et al Bronchiolitis obliterans syndrome (BOS) 27 anti-AEC Abs [41]
Goers et al Bronchiolitis obliterans syndrome (BOS) 36 anti-K-alpha1 tubulin Abs [42]
Tiriveedhi et al Bronchiolitis obliterans syndrome (BOS) N/A anti-K-alpha1 tubulin Abs [43]
Burlingham et al Bronchiolitis obliterans syndrome (BOS) collagen V [44]
Tirivedhi et al Bronchiolitis obliterans syndrome (BOS) 12 collagen V epitopes [45]
Liver Sumitran-Holgersson et al Rejection 95 Liver sinusoidal endothelial cells (LSECs) [37]
BMT Wadia et al GVHD 190 NuSAP1, CHAF1b [46]
Porcheray et al Rejection/tolerance 5 PSMA4 [52]

N/A* in vitro cell culture