Table 1.
Previous findings for MV growth and remodelling during pregnancy. All values previously reported in [5,12–14].
| NP average | P average | |
|---|---|---|
| leaflet stretch (under 60 N m−1) | ||
| circumferential stretch | 1.37 ± 0.03 | 1.26 ± 0.03 |
| radial stretch | 1.67 ± 0.06 | 1.67 ± 0.06 |
| leaflet surface dimensions | ||
| circumferential (cm) | 5.1 ± 0.1 | 5.9 ± 0.2 |
| radial (cm) | 2.5 ± 0.1 | 3.0 ± 0.1 |
| thickness (µm) | 1170 ± 75 | 1194 ± 59 |
| layer thicknesses (µm) | ||
| atrialis/spongiosa | 431 ± 85 | 346 ± 76 |
| fibrosa | 540 ± 130 | 833 ± 76 |
| ventricularis | 221 ± 40 | 135 ± 22 |
| constituent fractions (% dry wt) | ||
| total collagen | 56.7 ± 3.0 | 66.0 ± 3.3 |
| extractable collagen | 0.6 ± 0.1 | 0.6 ± 0.1 |
| elastin | 6.2 ± 0.6 | 2.8 ± 0.4 |
| GAGs | 3.3 ± 0.5 | 1.6 ± 0.2 |
| collagen crimp period (µm) | 22.9 ± 1.2 | 65 ± 15 |
| MVIC population density (per 0.1 mm2) | 10.2 ± 0.7 | 7.6 ± 0.7 |