Table 2.

Univariate associations (Pearson’s correlation coefficient) between brachial intima-media thickness and characteristics of patients with COPD and the complete sample

Subject characteristics	COPD		Smokers		Never-smokers
	r-value	P-value	r-value	P-value	r-value	P-value
Age, years	0.421	<0.001	0.408	0.074	0.468	0.037
Body mass index, m/kg2	0.131	0.321	−0.235	0.319	0.108	0.650
Smoking history, pack-years	0.046	0.732	0.331	0.154
Systolic blood pressure, mmHg	0.314	0.016	−0.101	0.672	0.224	0.357
Acute exacerbation rate, n/year	0.251	0.014
FEV1, % predicted	−0.185	0.160	0.303	0.194	0.181	0.445
FVC, % predicted	0.034	0.799	0.355	0.125	0.094	0.693
FEV1/FVC ratio	−0.286	0.028	0.115	0.631	−0.280	0.231
HbA1c, %	0.180	0.188	0.058	0.808	0.329	0.156
HDL/LDL ratio	0.047	0.69	0.376	0.151	0.440	0.115
Neutrophil count, ×103/mL	−0.056	0.681	0.018	0.943	0.278	0.235
Ln interleukin-6, pg/mL	0.365	0.006	0.229	0.346	−0.229	0.331
Ln pro-BNP, pg/mL	0.225	0.101	0.185	0.477	0.338	0.169
Ln ADMA, μmol/L	0.331	0.013	0.048	0.840	−0.283	0.226

Abbreviations: COPD, chronic obstructive pulmonary disease; FEV₁, forced expiratory volume in 1 s; FVC, forced vital capacity; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Ln, natural logarithm; Pro-BNP, pro b-type natriuretic peptide; ADMA, asymmetric dimethylarginine.