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. Author manuscript; available in PMC: 2017 Sep 14.
Published in final edited form as: J Am Chem Soc. 2016 Sep 2;138(36):11850–11859. doi: 10.1021/jacs.6b06454

Figure 1.

Figure 1

Chemical structure of HCV NS3/4A protease inhibitors. The three broad classes of HCV PIs: linear covalent and noncovalent (top row); P1–P3 macrocyclic (second row); and P2–P4 macrocyclic and P1–P3, P2–P4 bis-macrocyclic (third row).