Table 2.
General features of the studies included
| Studies | No of patients using clopidogrel + PPIs (n) | No of patients using clopidogrel alone (n) | Type of study | Region |
|---|---|---|---|---|
| Bhurke 2012 | 2958 | 7143 | Retrospective | United states |
| Burkard 2012 | 109 | 692 | Retrospective | United states |
| Chitose 2012 | 187 | 443 | Observational | Japan |
| Douglas 2012 | 12439 | 16900 | Observational | United Kingdom |
| Dunn 2013 | 408 | 9191 | Retrospective | Charlottesville |
| Goodman 2012 | 3255 | 6021 | RCT | Canada |
| Hsieh 2015 | 670 | 5933 | Observational | Taiwan |
| Macaione 2012 | 121 | 55 | Retrospective | Italy |
| Weisz 2015 | 2162 | 6419 | Observational | Israel |
| Zou 2014 | 6188 | 1465 | Observational | China |
| Gargiolo 2016 | 738 | 1232 | RCT | Italy |
| Total no of patients (n) | 29,235 | 55,494 |
Abbreviations: PPIs Proton pump inhibitor, RCT Randomized controlled trial