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. 2017 Jan 9;13(1):e1006525. doi: 10.1371/journal.pgen.1006525

Table 1. Phenotypic comparison of rib-1 and rib-2 mutant alleles.

Allele Molecular Lesion Overall phenotype of animals Reference
Homozygous M-/- Z-/- Maternally rescued M+/- Z-/-
rib-1 (tm516) 486 bp deletion and 32 bp insertion 99% of embryos die 1% die as first stage larvae Complete development to adulthood 54% adults defective for egg-laying [32]
rib-1 (ok556) 905 bp deletion Embryos and early larvae die Viable in this generation (no further information available) [33]
rib-1 (qm32) Stop to Lys 14% viable, become adults 100% of adults are defective for locomotion and egg-laying 32% of embryos die 80% of hatchlings die as larvae Fully rescued larvae and adults, no lethality Wild-type development, locomotion and egg-laying [54] This study
rib-2 (qa4900) 511 bp deletion 97% embryos die 3% remaining morphologically abnormal and die in first larval stage Adults defective for locomotion and egg-laying [34]
rib-2 (tm710) 1306 bp deletion Embryos die Viable in this generation (no further information available) [32, 33]
rib-2 (qm46) R434Q 63% viable, become adults 100% of adult are defective for locomotion and egg-laying 15% of embryos die 26% of hatchlings die as larvae Fully rescued larvae and adults, no lethality Wild-type development, locomotion and egg-laying [54] This study
rib-1 (qm32); rib-2 (qm46) Stop to Lys R434Q 100% embryos die Complete development to adulthood, but 100% adults are defective for locomotion and egg-laying This study