Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 30;12:217–237. doi: 10.2147/IJN.S122171

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Rui et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

The confocal microscopy images of MCF7/ADR cells after incubation with varying HMNs. The acid organelles in cells were stained by LysoTracker green (A). The HMNs containing FAM-labeled anti-miR21 (B) and FITC-labeled Apo AI proteins (C) were observed, respectively. Then the nucleus were stained with DAPI (blue) after fixation. Competitive inhibitory effect of natural HDL amounts on the accumulation levels of NLS-Dox in MCF7/ADR cells was determined by FACS analysis (D). Data are shown as mean ± SD (n = 3). **P<0.01.

Abbreviations: DAPI, 4′,6-diamidino-2-phenylindole; NLS, nuclear localization signal; Dox, doxorubicin; FAM, fluorescein-labeled anti-miR21; miR21, microRNA21; FITC, fluorescein isothiocyanate; HMNs, high-density lipoprotein-mimicking nanoparticles; HDL, high-density lipoprotein.