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Induction of cell apoptosis in MCF7/ADR cell treated with different formulations for 48 h. The apoptotic cells and necrotic cells were analyzed by flow cytometry.
Abbreviations: HMNs, high-density lipoprotein-mimicking nanoparticles; NLS, nuclear localization signal; Dox, doxorubicin; PI, propidium iodide; miR21, microRNA21; FITC, fluorescein isothiocyanate.
