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The qRT-PCR measurement of miR21 in MCF7/ADR cells after treating with different preparation for 48 h (A). And the protein expression levels of PTEN in MCF7/ADR cells after various treatments (B). The blank was untreated MCF7 cells without any other process. (n=3, error bars indicate SD, *P<0.05, **P<0.01).
Abbreviations: HMNs, high-density lipoprotein-mimicking nanoparticles; NLS, nuclear localization signal; Dox, doxorubicin; miR21, microRNA21.
