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. 2017 Jan 9;12(1):e0169675. doi: 10.1371/journal.pone.0169675

Fig 4. Inhibition of MMP-3 or MMP-13 activity reduced pterygium-derived fibroblast migration.

Fig 4

Pterygium fibroblasts were treated with an MMP-3 (1 μM) or MMP-13 (1 μM) inhibitor in serum-free medium, directly after the scratch wound. (A) Representative phase contrast microscopy images taken at 24 h and 48 h after a single uniform-width scratch wound of confluent pterygium fibroblasts. Dashed lines indicate the precise location of the scratch wound. Scale bar: 50 μm. (B) Pooled quantitative data of pterygium-derived fibroblast migration. Data were summarized as the mean ± standard deviation of 3 separate experiments. ***P < 0.001 vs control.