Table 3.
Patient IDa | Age at ARDS (months) | Prior Comorbidities | Not Intubated | Required HFOV or ECLS | Ventilator Data at time of diagnosisb
|
Intercurrent Respiratory ED visit or hospitalization | |||
---|---|---|---|---|---|---|---|---|---|
PIPc | MAPc | TV (mL/kg) | PaO2:FiO2 | ||||||
Obstructive Disease on Pulmonary Function Testing | |||||||||
5 | 59 | None | X | NA | NA | NA | 300 | None | |
6 | 130 | Reactive Airway Disease | 24 | 6.7 | 5.8 | 158 | None | ||
11 | 85 | Premature (no lung disease) | 24 | 8 | 7.1 | 271 | None | ||
13 | 39 | None | X | 37 | 211 | None | |||
Diffusion Capacity Abnormality | |||||||||
7 | 89 | Bone Marrow Transplant | X | 27 | 18 | 8.7 | 116 | fever unknown origin | |
16 | 176 | Reactive Airway Disease, Sickle Cell | X | NA | NA | NA | 56 | None | |
Normal Pulmonary Function Test | |||||||||
1 | 0.5 | Corrected Cardiac Defect | 34 | 9.6 | 9.4 | 68 | No data | ||
2 | 2 | Trisomy 21, corrected cardiac defect | 40 | 10.6 | 10.6 | 93 | None | ||
3 | 17 | None | 24 | 11 | 6.2 | 135 | No data | ||
4± | 40 | None | 267 | None | |||||
8 | 126 | None | 25 | 7.6 | 6 | 200 | None | ||
9 | 55 | Seizure disorder | 19 | 9.7 | 6.4 | 71 | None | ||
10 | 133 | None | 39 | 10 | 7 | 167 | None | ||
12 | 195 | Leukemia (not immunocompromised) | X | 25 | 37 | 7.1 | 240 | None | |
14 | 156 | None | X | NA | NA | NA | 167 | None | |
15 | 167 | None | X | NA | NA | NA | 293 | None | |
17§ | 37 | None | NA | NA | NA | 117 | None |
Patients with no details were not requiring invasive mechanical ventilation at the time;
Unit of measurement is cmH2O
Patient intubated en route to hospital but extubated within a few hours of admission;
Patient not intubated until 72 hours of ARDS
Abbreviations: HFOV = high frequency oscillatory ventilation; ECLS = Extracorporeal Life Support; PIP = Peak inspiratory pressure; PEEP = Positive end expiratory pressure; MAP = Mean airway pressure; TV = Tidal Volume