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. 2004 Nov;24(21):9527–9541. doi: 10.1128/MCB.24.21.9527-9541.2004

FIG. 10.

FIG. 10.

The ectopic expression of E2F1, but not cyclin D, can override the antiproliferative effects of penetratin-Raf-1 peptide conjugate. A549 and U2OS cells were infected with Ad-E2F1 or Ad-cyclin D in the presence or absence of 1 μM penetratin-Raf-1 peptide conjugate or scrambled peptide conjugate for 36 h. Cells infected with Ad-GFP were used as the control. (A and B) The S-phase entry of cells was quantitated by BrdU staining. (C and D) Western blot analysis of A549 cells and U2OS cells infected with the indicated adenoviral constructs show overexpression of E2F1 and cyclin D compared to control cells.