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. 2004 Oct 15;114(8):1090–1097. doi: 10.1172/JCI21055

Figure 4.

Figure 4

IgA dermal deposit localization. (A) FITC staining identifies IgA deposition in perilesional uninvolved areas of NOD Abo DQ8+ mice with gluten-dependent blistering. Original magnification, ×20. (B) Deposition of IgA at the tips of papillae. Original magnification, ×20. (C) Granularity of the IgA deposits below the basement membrane zone. Original magnification, ×100. (D) FITC staining identifies IgA. Original magnification, ×100. (E) Rhodamine Red-X staining identifies collagen IV. Original magnification, ×100. (F) Composite picture with both IgA staining and collagen IV staining. Original magnification, ×100. Arrows identify IgA deposits, and the basement membrane zone is highlighted by a dotted white line.