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. 2017 Jan 9;12(1):e0169528. doi: 10.1371/journal.pone.0169528

Table 3. Proportion of virus (sub)types/lineages (%) and vaccine mismatch per subtype/lineage based on virus isolates and specimens submitted to the NIC in week 40 of one year through week 39 of the following year, seasons 2003/04 through 2013/14, Netherlands.

Influenza season
Virus (sub)type 2003/04 2004/05 2005/06 2006/07 2007/08 2008/09 2009/2010 2010/11 2011/12 2012/13 2013/2014
Proportion of virus (sub) types (%)
A 99 80 64 99 49 92 100 60 90 69 94
A(H1N1)1 0 18 4 13 86 1 100 97 1 39 40
A(H3N2) 100 82 96 87 14 99 0 3 99 61 60
B 1 20 36 1 51 8 0 40 10 31 6
B Y Y Y/V Y Y V NA Y/V Y/V Y/V Y/V
B/Vic 91 95 12 6 24
B/Yam 9 5 88 94 76
Mismatch per subtype
A(H3N2) Yes Yes No No No No NA No Yes Yes Yes
A(H1N1)1 NA No No Yes Yes No Yes2 No No No No
B/Vic NA NA Yes (Yam in vaccine) NA NA Yes (Yam in vaccine) NA No No NA NA
B/Yam Yes (Vic in vaccine) Yes (Antigenic mismatch) Yes (Antigenic mismatch) Yes(Vic in vaccine) Yes (Vic in vaccine) NA NA Yes (Antigenic mismatch) Yes (Vic in vaccine) Yes (Antigenic mismatch) Yes (Antigenic mismatch)
Vaccine mismatch Mismatch Mismatch Partially match Partially match Mismatch Match Mismatch Match Mismatch Mismatch Mismatch

V: B/Victoria/2/87-lineage; Y: B/Yamagata/16/88-lineage; NA: Not applicable.

12003/2004 through 2008/2009 season former seasonal A(H1N1); 2009/2010 through 2013/2014 season A(H1N1)pdm09.

2Seasonal A(H1N1) was used in the vaccine; A(H1N1)pdm09 monovalent vaccine was available late in the 2009/10 influenza season.