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. 2016 Dec 27;10(12):e0005259. doi: 10.1371/journal.pntd.0005259

Table 1. Comparison of the virulence genes of the uncharacterized CU strains to that of 35000HP and CIP542.

Class I CU strains Class II CU strains
VAN1 VAN3 VAN4 VAN5 GHA3 GHA5 GHA8 GHA9 VAN2 GHA1 GHA2
cpxA 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542
csrA* 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP
dksA 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542
dltA 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542
dsrA A1 A1 A1 A1 A2 A2 A3 A3 B B B
fgbA 35000HP 35000HP 35000HP 35000HP A A 35000HP 35000HP CIP542 CIP542 CIP542
flp1 A A A A A A A A CIP542 CIP542 CIP542
flp2 A A A A A A A A CIP542 CIP542 CIP542
flp3 A A A A A A A A CIP542 CIP542 CIP542
hfq 35000HP 35000HP 35000HP 35000HP A A 35000HP 35000HP CIP542 CIP542 CIP542
hgbA 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542
lspA1 A A A A A A A A - - -
lspA2 A A A A A A A A - - -
luxS* A A A A A A A A CIP542 CIP542 CIP542
ncaA A A A A A A 35000HP 35000HP CIP542 CIP542 CIP542
pal 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542
relA A A A A A A A A CIP542 CIP542 CIP542
sapA 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542
sapB 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542
sapC A A A A A A A A CIP542 CIP542 CIP542
spoT 35000HP 35000HP 35000HP 35000HP A A A A CIP542 CIP542 CIP542
tadA 35000HP 35000HP 35000HP 35000HP A A 35000HP 35000HP CIP542 CIP542 CIP542
wecA 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP 35000HP CIP542 CIP542 CIP542

35000HP, the nucleotide sequence is identical to that of 35000HP.

CIP542, the nucleotide sequence is identical to that of CIP542.

*, the csrA and luxS alleles of 35000HP and CIP542 are identical

A, the nucleotide sequence differs from 35000HP by at least 1 nucleotide but is identical within the class I CU strains; A1, A2, and A3 designate groups of strains with dsrA alleles that also differ from each other.

B, the nucleotide sequence is different from CIP542 by at least 1 nucleotide but is identical within the class II CU strains.

-, complete sequence not available for CIP542 and therefore, no comparison with the class II CU strains.