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. Author manuscript; available in PMC: 2017 Jan 9.
Published in final edited form as: Immunity. 2016 Jul 19;45(1):74–82. doi: 10.1016/j.immuni.2016.06.024

Figure 2. Ly49D and Ly49A Enhance Activation and IFN-γ Production of B10.D2 Ly49H+ NK Cells in the Early Course of MCMV Infection.

Figure 2

B6 mice were infected with 1 × 104 pfu MCMV. B10.D2 mice were depleted of CD8+T cells onthe day before infection and theninfected with 5×104 pfu MCMV.

(A) IFN-γ production of Ly49H+ NK cell subsets expressing Ly49D and or Ly49A in the spleen on day 1.5 pi. Data are representative of two experiments (n = 3–4 in each experiment).

(B) Delta mean fluorescent intensity (ΔMFI) of IFN-γ in Ly49H+ NK cells was quantified. Data were pooled from two experiments (n = 7 mice in each group). Bold and thin lines represent Ly49H+ NK cells in infected mice and Ly49H+ NK cells in uninfected mice, respectively. *p < 0.05. Error bars show SEM.