Table 1.
Patients’ demographic and clinical characteristics
| Variables | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Median (IQR) |
|---|---|---|---|---|---|---|---|---|
| Age (years) | 75 | 45 | 44 | 73 | 62 | 68 | 77 | 68.0 (20.5) |
| Sex | M | M | M | M | M | M | F | |
| BMI (kg/m2) | 26.3 | 29.4 | 29 | 29.1 | 21.3 | 24.7 | 44 | 29.0 (3.8) |
| Comorbidity | COPD, DM2, hypertension | DVT | OSAS | Hypertension, hypothyroidism | Hypertension | CAD (stented) | CAD (stented) | |
| Tumor histology | SCC | ADC | SCC | ADC | ADC | ADC | ADC | |
| Neoadjuvant therapy | CRT | CRT | CRT | None | CRT | CRT | CRT | |
| pTNM | T2N0M0 | T2N1M0 | T2N3M0 | T3N2M0 | T2N1M0 | T3N1M0 | T2N0M0 | |
| ASA score | 3 | 2 | 2 | 3 | 2 | 2 | 3 | 2.0 (1.0) |
| Indication to SAP | TEA technical failure | Anticoagulation therapy | Unplanned thoracotomy | TEA technical failure | Antiaggregation therapy | Antiaggregation therapy | TEA technical failure | |
| Operative time (minutes) | 235 | 300 | 385 | 295 | 300 | 325 | 270 | 300.0 (30.0) |
| Static VAS | ||||||||
| POD 1 | 40 | 0 | 15 | 15 | 20 | 35 | 30 | 20 (17.5) |
| POD 2 | 20 | 0 | 10 | 15 | 10 | 30 | 20 | 15 (10) |
| POD 3 | 10 | 0 | 0 | 0 | 0 | 10 | 0 | 0 (5) |
| POD 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 (0) |
| Dynamic VAS | ||||||||
| POD 1 | 50 | 15 | 20 | 25 | 15 | 50 | 30 | 25 (22.5) |
| POD 2 | 40 | 0 | 15 | 10 | 10 | 25 | 30 | 15 (17.5) |
| POD 3 | 20 | 0 | 0 | 0 | 0 | 0 | 10 | 0 (5) |
| POD 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0(0) |
| Rescue analgesia | ||||||||
| POD 1 | Remifentanil | Remifentanil | Remifentanil | |||||
| PODs 2–3 | Naropin | Ketorolac | ||||||
| ICU stay (days) | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 (1) |
| Hospital stay (days) | 10 | 10 | 10 | 10 | 20 | 7 | 8 | 10.0 (1.5) |
| Follow up (months) | 6 | 5 | 5 | 4 | 3 | 2 | 2 | 5 (2) |
Abbreviations: ADC, adenocarcinoma; ASA, American Society of Anesthesiologists; BMI, body mass index; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; CRT, chemoradiation therapy; CT, chemotherapy; DM2, diabetes mellitus type 2; DVT, deep vein thrombosis; F, female; ICU, intensive care unit; IQR, interquartile range; M, male; OSAS, obstructive sleep apnea syndrome; POD, postoperative day; pTNM, pathological tumor–node–metastasis; SAP, serratus anterior plane; SCC, squamous cell carcinoma; TEA, thoracic epidural analgesia; VAS, visual analog scale.