Table 5.
Attributable risk of incident high-risk HPV DNA detection due to type-specific HPV serostatus and cumulative and recent sexual behavior among mid-adult women, Seattle, WA, 2011–2012
| Characteristic | Na | nb | aORc | (95% CI) | %ARd | %PARe |
|---|---|---|---|---|---|---|
| Overall | ||||||
|
| ||||||
| Seronegative, not sexually active OR sexually active and no risk factorsf | 10,727 | 10 | 1.0 | -- | ||
| Seronegative, sexually active and ≥ 1 risk factorf | 9,412 | 38 | 4.5 | (2.1, 9.6) | 77.6 | 39.8 |
| Seropositive | 4,093 | 26 | 6.9 | (3.0, 15.9) | 85.4 | 30.0 |
|
| ||||||
| Ages 30–39 | ||||||
|
| ||||||
| Seronegative, not sexually active OR sexually active and no risk factorsf | 6,110 | 5 | 1.0 | -- | ||
| Seronegative, sexually active and ≥ 1 risk factorf | 5,924 | 30 | 5.9 | (2.1–16.6) | 83.0 | 47.9 |
| Seropositive | 2,236 | 17 | 8.3 | (2.8–24.4) | 87.9 | 28.7 |
|
| ||||||
| Ages 40–50 | ||||||
|
| ||||||
| Seronegative, not sexually active OR sexually active and no risk factorsf | 4,617 | 5 | 1.0 | -- | ||
| Seronegative, sexually active and ≥ 1 risk factorf | 3,488 | 8 | 2.3 | (0.7–8.3) | 57.4 | 20.9 |
| Seropositive | 1,857 | 9 | 4.6 | (1.2–17.9) | 78.3 | 32.0 |
Indicates the total number of women-types * number of samples included in each stratum
Indicates the number of women-types * number of samples with incident HPV detected
Adjusted for age, marital status, ever had non-HPV-related STDs, and lifetime number of sex partners in tertiles for overall results; not adjusted for age in age-stratified results.
Attributable risk percent calculated as [(OR – 1) / OR] * 100
Population attributable risk percent calculated as {pd * [(OR – 1) / OR]} * 100, where pd is the proportion of cases exposed to the risk factor
Risk factors include ≥1 new sex partner, multiple partners (>1 sex partners), ≥1 casual partner, ≥1 partner with other concurrent partners, and ≥1 partner with a history of STDs.