Table 1.
Lipid mediator analysis in acute inflammation model
| No Stretch | Stretch | |
|---|---|---|
| DHA bioactive metabolome | ||
| Rv D1 | 0.04±0.007 | 0.06±0.01 |
| RvD2 | 0.04±0.01 | 0.06±0.02 |
| RvD3 | 0.01±0.0005 | 0.02±0.004 |
| RvD5 | * | * |
| RvD6 | * | * |
| AT-RvD1 | 0.01±0.004 | 0.01±0.009 |
| AT-RvD3 | 0.004±0.0007 | 0.006±0.001 |
| PD1 | * | * |
| 10S, 17S-diHDHA | 0.02±0.01 | 0.03±0.005 |
| MaRr1 | 0.04±0.009 | 0.04±0.005 |
| 7S,14S-diHDHA | * | * |
| EPA bioactive metabolome | ||
| RvE1 | * | * |
| RvE2 | * | * |
| RvE3 | 0.01±0.002 | 0.02±0.01 |
| AA bioactive metabolome | ||
| LXA4 | * | * |
| LXB4 | 0.2±0.04 | 0.2±0.1 |
| 5S, 15S-diHETE | 0.5±0.1 | 0.4±0.1 |
| AT-LXA4 | 0.9±0.02 | 0.1±0.06 |
| AT-LXB4 | * | * |
| LTB4 | 0.5±0.2 | 0.2±0.09 |
| 5S,12S-diHETE | * | * |
| 20-OH-LTB4 | * | * |
| 20-COOH-LTB4 | * | * |
| PGD2 | 7.7±2.5 | 7.7±5.3 |
| PGE2 | 17.2±2.6 | 14.8±5.9 |
| PGF2a | 1.5±0.5 | 1.3±0.9 |
| TXB2 | 8.6±3.1 | 11.7±8.2 |
Results are expressed as mean ± SE, normalized to the inflammatory lesion cross sectional area (n=4/group).
*
, Below Limit, limit ~0.1pg.