Effect of DGCR8 Depletion on Co-transcriptional Processing
mNET-seq/S5P profiles for (A) CCND1, (B) MIR17HG-GPC5, (C) MALAT1, and (D) LINC01021 with DGCR8 siRNA-mediated depletion or control siLuc treatment. Orange arrow indicates loss of pre-miRNA cleavage for MIR17HG or elevated levels of cleavage products following DGCR8 depletion for MALATI and LINC01021. Duplicate mNET-seq/S5Ps are presented to underline data reproducibility.
See also Figure S6.