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Measurement of (A–D) enzymatic activities of mitochondrial respiratory chain complexes (CS, I, II, IV) in liver from ERα WT and KO mice receiving normal diet (SD), western diet (WD), or SD and WD containing polyphenols (SD + polyphenols and WD + polyphenols, respectively) during 12 weeks. The data are expressed as the mean ± SEM. Statistical analyses were performed by one-way ANOVA and Holm–Sidak’s post hoc test, **P < 0.01.
