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. 2017 Jan 10;7:537. doi: 10.3389/fphar.2016.00537

Table 2.

Effects on testis extratubular compartment for the two types of control animals (Control plus vehicle; Control plus PDRN) and the two types of treated ones (CdCl2 plus vehicle; CdCl2 plus PDRN).

Extratubular compartment
Edema Hemorrhagic extravasation Vascular dilation Leydig cells changes
Control plus vehicle 0 0 0 0
Control plus PDRN 0 0 0 0
CdCl2 plus vehicle 1.4 ± 0.3a 1.8 ± 0.3a 1.7 ± 0.4a 1.3 ± 0.2a
CdCl2 plus PDRN 0.7 ± 0.3b 0.8 ± 0.3b 0.7 ± 0.3b 0.4 ± 0.3b

ap < 0.05 vs. control; bp < 0.05 vs. CdCl2 plus vehicle. Histologic grading of the extratubular compartment changes was based on the following scale: 0, absent; 1, mild; 2, moderate; 3, severe.