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. 2017 Jan 10;10:252. doi: 10.3389/fnbeh.2016.00252

Figure 1.

Figure 1

Age-matched sleep behavior in MSA mice vs. control animals. (A,B,D,E) WAKE and NREMS is generally very similar in young MSA mice and young control animals (FWake = 5.997, p = 0.015; FNREMS = 5.997, p = 0.015) and adult (FWake = 0.0000768, p = 0.993; FNREMS = 0.321, p = 0.572). (C,F) Significant differences between MSA mice and control animals in REMS, detected around 10 (F = 17.336, p < 0.001) clearly decrease in adult mice (F = 10.397, p = 0.002). For all graphs shown: X-axis represents the experimental time of one 24 h-recording session, Y-axis represents the amount of the behavioral state WAKE, NREMS, and REMS. White background: inactive period/lights on (hour 0 to hour 12), gray background: active period/lights off (hour 12 to hour 24). All data are 2 h means ± SEM, Two way ANOVA, followed by Bonferroni corrections (p ≤ 0.05). Number of animals: nMSAyoung = 8, nMSAadult = 10, nControlyoung = 8, nControladult = 6.