Table 1.
Correlations between type-2 inflammatory mediators and tissue eosinophilia or radiographic severity
| Type-2 inflammatory mediators | ECP in UT (Total Subjects*) | CT scores (Patients with CRSwNP†) | |||
|---|---|---|---|---|---|
| r | P-value | r | P-value | ||
| in UT | |||||
| IL-13 | 0.84 | <0.0001 | 0.49 | 0.002 | |
| Eotaxin-1 | 0.19 | 0.31 | 0.34 | 0.04 | |
| Eotaxin-2 | 0.70 | <0.0001 | 0.60 | 0.0002 | |
| Eotaxin-3 | 0.54 | 0.002 | 0.34 | 0.049 | |
| ECP | - | - | 0.58 | 0.0003 | |
| in Nasal Lavage Fluid | |||||
| IL-13 | 0.55 | 0.001 | 0.11 | 0.41 | |
| Eotaxin-1 | 0.12 | 0.52 | 0.09 | 0.49 | |
| Eotaxin-2 | 0.51 | 0.003 | 0.15 | 0.29 | |
| Eotaxin-3 | 0.49 | 0.004 | 0.14 | 0.31 | |
| ECP | 0.26 | 0.30 | 0.05 | 0.81 | |
ECP, eosinophil cationic protein; UT, uncinate tissue; CT, computed tomography; CRSwNP, chronic rhinosinusitis with nasal polyps
*
N= 32 for correlations between ECP in UT with measures in UT and nasal lavage fluid
†
N= 34 and 55 for correlations between CT scores with measures in UT and nasal lavage fluid respectively; UT tissue was not always available in instances of revision surgery.