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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Immunol Lett. 2016 Nov 22;181:58–62. doi: 10.1016/j.imlet.2016.11.011

Table 4.

GWA dataset analysis for CCDC22 SNP rs2294020 in patients affected by different autoimmune diseases, including myotrophic lateral sclerosis and type-2 diabetes (MAF, Minor allele frequency; for other abbreviations refer to text).

Disease MAF
cases
MAF
controls
MF02 MF01 MFcomb Fisher MFcomb Stouffer
Amyotrophic Lateral Sclerosis (Finland) 0.3449 0.3640 0.642 0.541 0.819 0.539
Amyotrophic Lateral Sclerosis (Irish) 0.2943 0.2743 0.501 0.596 0.781 0.579
Celiac disease 0.2723 0.2902 0.793 0.580 0.598 0.559
Multiple Sclerosis 0.2491 0.2681 0.140 0.191 0.303 0.206
Multiple Sclerosis (WT2) 0.2812 0.2712 0.084 0.034 0.090 0.030
Vitiligo (GWAS1) 0.2593 0.3075 0.013 0.018 0.040 0.016
Vitiligo (GWAS2) 0.2362 0.2787 0.044 0.023 0.071 0.051
Chron's disease (NIDDK) 0.2929 0.2679 0.658 0.438 0.470 0.417
Chron's disease (WT) 0.2684 0.2546 0.439 0.485 0.729 0.498
Psoriasis 0.2536 0.2846 0.027 0.039 0.077 0.038
Type-2 Diabetes (GENEVA) 0.2815 0.2733 0.503 0.375 0.671 0.381
Type-2 Diabetes (WT) 0.2843 0.2689 0.202 0.389 0.346 0.425
Type-1 Diabetes 0.2663 0.2674 0.255 0.390 0.466 0.445
Rheumatoid Arthritis 0.2581 0.2676 0.374 0.626 0.444 0.633
Ankylosing Spondylitis 0.2692 0.2706 0.211 0.685 0.024 0.625
Ulcerative Colitis 0.2751 0.2705 0.548 0.769 0.564 0.797