Table 2.
Product | AUC0–36 h (ng h/mL) | C max (ng/mL) | ||
---|---|---|---|---|
Mean ± SEMa | Geometric mean ± SEMb | Mean ± SEM | Geometric mean ± SEM | |
R 1 | 26.75 ± 3.85 | 16.23 ± 1.19 | 1.32 ± 0.18 | 0.85 ± 1.18 |
R 2 | 26.32 ± 4.07 | 16.34 ± 1.18 | 1.29 ± 0.17 | 0.86 ± 1.17 |
T | 25.38 ± 4.52 | 13.84 ± 1.20 | 1.12 ± 0.19 | 0.67 ± 1.19 |
AUC area under the curve, C max maximum plasma concentration, R reference SEM standard error of the mean, T test product
aMean refers to the arithmetic mean and corresponds to the arithmetic mean profiles in Fig. 2
bGeometric mean refers to the geometric mean that was used in the statistical evaluation reported in Table 1