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Effect of storage time on dissolution parameters of propranolol PEO tablet matrices
| PEO | Time (weeks) | DE (%) | MDT(h) |
|---|---|---|---|
| 750 | 0 | 75.0 ± 2.81 | 2.59 ± 1.24 |
| 750 | 2 | 84.0 ± 4.0 | 1.81 ± 0.26 |
| 750 | 4 | 88.0 ± 0.83 | 1.48 ± 0.04 |
| 750 | 8 | 92.0 ± 0.26 | 0.96 ± 0.03 |
| 303 | 0 | 60.0 ± 4.06 | 3.93 ± 0.07 |
| 303 | 2 | 68.0 ± 1.68 | 3.72 ± 0.03 |
| 303 | 4 | 85.0 ± 1.15 | 1.93 ± 0.02 |
| 303 | 8 | 91.0 ± 0.93 | 1.16 ± 0.01 |
DE dissolution efficiency, MDT mean dissolution time
