Table 5.
The best emulsification process parameters obtained based on regression trees with measured and observed physicochemical properties of the obtained nanoemulsions
| Run | Independent variables | Dependent variables | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T = 1 day | t = 60 days | |||||||||||
| Type of surfactant, Em-ra | Emulsifier concentration, Em-c (%) | Speed of stirring, rpm | Pre-emulsification time, premix time (min) | Output power of ultrasounds, M (%) | Droplet size, d (nm) (mean ± SD) | Polydispersity index (PDI) | Multi-modality, n(I) | Viscosity for 50 1/s, η (mPa·s) (mean ± SD) | Visual observation (VO) | Droplet size, d (nm) (mean ± SD) | Polydispersity index (PDI) | |
| 26 | 0 | 4 | 100 | 10 | 20 | 189.0 ± 5 | 0.216 | 1 | 580 ± 50 | Homogeneous | 233 ± 12 | 0.325 |
| 27 | 0 | 4 | 300 | 10 | 20 | 179.8 ± 10 | 0.303 | 1 | 562 ± 30 | Homogeneous | 168 ± 9 | 0.232 |
| 28 | −1 | 4 | 300 | 15 | 60 | 191.1 ± 9 | 0.335 | 1 | 690 ± 100 | Homogeneous | 201 ± 3 | 0.269 |
| 29 | −1 | 6 | 100 | 10 | 40 | 159.5 ± 8 | 0.257 | 2 | 587 ± 22 | Homogeneous | 164 ± 6 | 0.295 |
aEm-r: −1 polysorbate 80, 0 decyl glucoside