Table 1.
Median (range) | % | |
---|---|---|
Age (years) | 69 (61–85) | |
Gender | ||
Male | 61 | |
Female | 39 | |
Number of previous regimens | 4 (1–7) | |
ECOG | ||
0 | 43 | |
1 | 48 | |
2 | 9 | |
Rai stage | ||
I | 26 | |
II | 4 | |
III | 26 | |
IV | 44 | |
Cytogenetic abnormality | ||
17p- or TP53 mutation | 43 | |
11q- | 30 | |
13q- | 52 | |
12+ | 13 | |
Normal | 17 | |
Lymph nodes >5 cm | 48 | |
Unmutated IgHV gene | 73 | |
Refractory to fludarabine or bendamustine | 56 |