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. 2016 Oct;186(10):2761–2768. doi: 10.1016/j.ajpath.2016.06.016

Figure 5.

Figure 5

CSE1L shRNA interference in HCT116, HT29, and SW480 cell line proliferation and survival. A: CSE1L shRNA interference in human colorectal cancer cells leads to significant inhibition of proliferation. B: Cell colonies treated with CSE1L shRNA show significant reduction in anchorage-independent growth versus colonies treated with control shRNA. C: shRNA causes significant induction of apoptosis, as measured by death cell enzyme-linked immunosorbent assay in HCT116, HT29, and SW480 cell lines compared to the mock and scramble shRNA groups. ∗P < 0.05, ∗∗P < 0.01.