Table 2.
Results of the Cox regression to identify independent potential variables influencing overall survival of patients undergoing resection for duodenal adenocarcinoma.
| Characteristics | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| Hazard ratio | p value | Hazard ratio | p value | |
| Age∗ | 1.53 (0.92–2.54) | 0.100 | ||
| Gender (male versus female) | 1.56 (0.94–2.58) | 0.087 | ||
| BMI∗ | 0.80 (0.55–1.67) | 0.246 | ||
| Tumor size∗ | 0.56 (0.29–1.11) | 0.098 | ||
| Tumor location∗ | 0.84 (0.43–1.61) | 0.589 | ||
| T stage∗ | 1.84 (1.35–2.52) | <0.001 | 1.05 0.58–1.92 | 0.866 |
| Differentiation∗ | 0.79 (0.66–0.95) | 0.013 | 0.84 0.65–1.10 | 0.210 |
| Vascular invasion (yes versus no) | 3.71 (1.94–7.08) | <0.001 | 3.75 1.24–11.39 | 0.020 |
| Perineurial invasion (yes versus no) | 2.19 (1.05–4.55) | 0.036 | 0.49 0.16–1.49 | 0.211 |
| Lymph node metastasis (yes versus no) | 5.77 (3.32–10.02) | <0.001 | 31.76 2.14–470.8 | 0.012 |
| TNM stage∗ | 1.94 (1.49–2.52) | <0.001 | 0.51 0.18–1.45 | 0.207 |
| CEA level (elevated versus normal) | 2.09 (1.07–4.09) | 0.032 | 1.26 0.41–3.88 | 0.689 |
| Transfusion (yesversus no) | 1.16 (0.70–1.93) | 0.560 | ||
| Recurrence and metastasis (yes versus no) | 4.66 (2.73–7.96) | <0.001 | 1.67 0.65–4.28 | 0.281 |
| Adjuvant therapy (yes versus no) | 1.25 (0.75–2.09) | 0.389 | ||
∗Analyzed as continuous variable.