Table 2.
Results of overall and subgroups analyses.
| No | T versus C | TT versus CC | TC versus CC | TT versus TC + CC | TT + TC versus CC | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR [95% CI] | P(Z) | P a | OR [95% CI] | P(Z) | P a | OR [95% CI] | P(Z) | P a | OR [95% CI] | P(Z) | P a | OR [95% CI] | P(Z) | P a | ||
| Gastric cancer | ||||||||||||||||
| Total | 9 | 1.12 [1.01, 1.25] | 0.04 | 0.46 | 1.12 [0.79, 1.58] | 0.52 | 0.20 | 1.16 [1.02, 1.33] | 0.02 | 0.58 | 1.05 [0.75, 1.48] | 0.78 | 0.15 | 1.16 [1.02, 1.32] | 0.02 | 0.64 |
| HWE, yes | 7 | 1.01 [0.70, 1.45] | 0.96 | <0.01 | 1.42 [0.95, 2.12] | 0.08 | 0.42 | 1.16 [1.00, 1.34] | 0.06 | 0.68 | 1.36 [0.89, 2.07] | 0.16 | 0.40 | 1.18 [1.02, 1.36] | 0.02 | 0.60 |
| HWE, no | 2 | 0.99 [0.79, 1.25] | 0.96 | 0.64 | 0.57 [0.28, 1.16] | 0.12 | 0.69 | 1.19 [0.76, 1.85] | 0.45 | 0.11 | 0.51 [0.26, 1.03] | 0.06 | 0.56 | 1.10 [0.81, 1.48] | 0.54 | 0.27 |
| Caucasian | 3 | 1.01 [0.84, 1.21] | 0.94 | 0.88 | 0.66 [0.35, 1.22] | 0.18 | 0.63 | 1.13 [0.91, 1.40] | 0.28 | 0.23 | 0.60 [0.33, 1.12] | 0.11 | 0.52 | 1.07 [0.87, 1.32] | 0.50 | 0.52 |
| Asian | 6 | 1.19 [1.04, 1.37] | 0.01 | 0.38 | 1.46 [0.96, 2.22] | 0.08 | 0.32 | 1.18 [1.00, 1.40] | 0.04 | 0.63 | 1.38 [0.91, 2.09] | 0.13 | 0.29 | 1.21 [1.03, 1.42] | 0.02 | 0.56 |
| HB | 4 | 1.09 [0.93, 1.28] | 0.28 | 0.15 | 1.04 [0.46, 2.34] | 0.93 | 0.04 | 1.17 [0.96, 1.42] | 0.12 | 0.42 | 0.98 [0.42, 2.27] | 0.96 | 0.03 | 1.14 [0.95, 1.38] | 0.16 | 0.41 |
| PB | 5 | 1.15 [0.99, 1.34] | 0.06 | 0.71 | 1.34 [0.77, 2.32] | 0.30 | 0.71 | 1.16 [0.97, 1.38] | 0.10 | 0.44 | 1.26 [0.73, 2.18] | 0.40 | 0.65 | 1.17 [0.99, 1.39] | 0.07 | 0.54 |
| PCR | 3 | 1.22 [0.99, 1.50] | 0.06 | 0.50 | 1.82 [0.89, 3.75] | 0.10 | 0.90 | 1.17 [0.91, 1.49] | 0.22 | 0.24 | 1.73 [0.84, 3.54] | 0.13 | 0.83 | 1.21 [0.96, 1.54] | 0.11 | 0.31 |
| PCR-RFLP | 3 | 1.16 [0.83, 1.61] | 0.38 | 0.08 | 1.10 [0.32, 3.77] | 0.88 | 0.02 | 1.21 [0.94, 1.55] | 0.13 | 0.27 | 1.03 [0.29, 3.67] | 0.97 | 0.01 | 1.18 [0.93, 1.50] | 0.16 | 0.26 |
| TaqMan | 3 | 1.07 [0.90, 1.26] | 0.44 | 0.89 | 0.89 [0.49, 1.61] | 0.70 | 0.89 | 1.13 [0.93, 1.38] | 0.22 | 0.63 | 0.85 [0.47, 1.53] | 0.59 | 0.84 | 1.11 [0.92, 1.35] | 0.28 | 0.73 |
| HCC | ||||||||||||||||
| Total | 4 | 1.16 [0.89, 1.51] | 0.27 | 0.08 | 1.65 [1.06, 2.57] | 0.03 | 0.14 | 1.10 [0.90, 1.34] | 0.35 | 0.33 | 1.61 [1.04, 2.49] | 0.03 | 0.19 | 1.16 [0.96, 1.40] | 0.13 | 0.16 |
| HWE, yes | 3 | 1.16 [0.77, 1.77] | 0.48 | 0.05 | 2.29 [1.16, 4.51] | 0.02 | 0.14 | 1.13 [0.87, 1.48] | 0.37 | 0.19 | 2.21 [1.12, 4.34] | 0.02 | 0.20 | 1.22 [0.94, 1.57] | 0.13 | 0.09 |
| HB | 2 | 1.32 [0.90, 1.94] | 0.15 | 0.04 | 2.13 [0.68, 6.67] | 0.19 | 0.04 | 1.19 [0.95, 1.50] | 0.14 | 0.24 | 2.00 [0.70, 5.69] | 0.20 | 0.05 | 1.30 [0.90, 1.87] | 0.16 | 0.10 |
| PB | 2 | 0.93 [0.66, 1.29] | 0.65 | 0.90 | 1.06 [0.36, 3.09] | 0.92 | 0.51 | 0.87 [0.59, 1.30] | 0.51 | 0, 59 | 2.00 [0.70, 5.69] | 0.86 | 0.48 | 0.89 [0.61, 1.31] | 0.56 | 0.72 |
| PCR | 2 | 1.08 [0.86, 1.35] | 0.51 | 0.66 | 1.20 [0.66, 2.17] | 0.55 | 0.47 | 1.05 [0.80, 1.39] | 0.71 | 0.90 | 1.18 [0.66, 2.12] | 0.58 | 0.47 | 1.07 [0.83, 1.39] | 0.60 | 0.78 |
| PCR-RFLP | 2 | 1.24 [0.70, 2.18] | 0.46 | 0.02 | 2.35 [0.73, 7.51] | 0.15 | 0.11 | 1.10 [0.64, 1.89] | 0.74 | 0.07 | 2.45 [1.22, 4.93] | 0.01 | 0.17 | 1.18 [0.65, 2.18] | 0.58 | 0.04 |
| Colorectal cancer | ||||||||||||||||
| Total | 4 | 1.01 [0.80, 1.27] | 0.94 | 0.45 | 0.99 [0.40, 2.41] | 0.97 | 0.62 | 1.01 [0.78, 1.31] | 0.93 | 0.45 | 1.01 [0.41, 2.45] | 0.99 | 0.69 | 1.01 [0.78, 1.30] | 0.93 | 0.43 |
| African | 2 | 0.94 [0.68, 1.29] | 0.69 | 0.85 | 0.83 [0.27, 2.54] | 0.75 | NA | 0.94 [0.65, 1.36] | 0.75 | 0.86 | 0.88 [0.29, 2.67] | 0.82 | NA | 0.93 [0.65, 1.34] | 0.71 | 0.85 |
| Caucasian | 2 | 1.01 [0.58, 1.76] | 0.97 | 0.14 | 1.34 [0.30, 6.05] | 0.70 | NA | 1.00 [0.54, 1.85] | 1.00 | 0.13 | 1.29 [0.29, 5.84] | 0.74 | NA | 1.00 [0.54, 1.86] | 0.99 | 0.12 |
| HB | 3 | 1.06 [0.76, 1.48] | 0.72 | 0.33 | 1.34 [0.30, 6.05] | 0.70 | NA | 1.07 [0.77, 1.49] | 0.69 | 0.31 | 1.29 [0.29, 5.84] | 0.74 | NA | 1.08 [0.78, 1.49] | 0.65 | 0.30 |
| PB | 1 | 0.92 [0.65, 1.31] | 0.66 | NA | 0.83 [0.27, 2.54] | 0.75 | NA | 0.93 [0.61, 1.41] | 0.72 | NA | 0.88 [0.29, 2.67] | 0.82 | NA | 0.92 [0.61, 1.38] | 0.68 | NA |
| PCR | 1 | 0.71 [0.36, 1.38] | 0.31 | NA | NA | NA | NA | 0.68 [0.34, 1.38] | 0.29 | NA | NA | NA | NA | 0.68 [0.34, 1.38] | 0.29 | NA |
| TaqMan | 3 | 1.06 [0.83, 1.35] | 0.65 | 0.49 | 0.99 [0.40, 2.41] | 0.97 | 0.62 | 1.08 [0.81, 1.43] | 0.60 | 0.54 | 1.01 [0.41, 2.45] | 0.99 | 0.69 | 1.07 [0.82, 1.41] | 0.61 | 0.50 |
| Cervical cancer | ||||||||||||||||
| Total | 3 | 0.75 [0.44, 1.29] | 0.30 | 0.003 | 0.59 [0.23, 1.54] | 0.28 | 0.11 | 0.77 [0.42, 1.42] | 0.40 | 0.01 | 0.81 [0.47, 1.39] | 0.44 | 0.20 | 0.75 [0.40, 1.40] | 0.36 | 0.005 |
| Prostate cancer | ||||||||||||||||
| Total | 2 | 1.05 [0.89, 1.24] | 0.57 | 0.11 | 1.20 [0.62, 2.35] | 0.59 | 0.74 | 1.04 [0.86, 1.25] | 0.68 | 0.08 | 1.16 [0.60, 2.27] | 0.66 | 0.85 | 1.05 [0.87, 1.25] | 0.62 | 0.08 |
P a was derived from Chi-square statistics.