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Protective effect of Cyr61 in hypoxia induced HK-2 apoptosis. (a) The changes of Cyr61 protein level after transfection. (b) Quantitative assessment of apoptotic cells by annexin V FITC/PI staining. (c) The changes of cleaved Caspase-3 protein level. Data were presented as the mean ± SD (n = 5 per group). ∗∗ P < 0.01 and ∗∗∗ P < 0.001 versus control group. & P < 0.05 and &&& P < 0.001 versus hypoxia alone (empty plasmid) group.
