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Overexpression of Cyr61 downregulated CHOP protein level. (a) mRNA expression level of GRP78 and CHOP upon Cyr61 overexpression in hypoxia cultured HK-2 cells. (b) The changes of CHOP protein level with overexpression of Cyr61. Data were presented as the mean ± SD (n = 4 per group). ∗∗ P < 0.01 versus hypoxia alone (empty plasmid) group.
