Figure 3.
Boxplots of Interleukin-16 Cytokine and IL16 mRNA Concentrations
The mRNA and circulating cytokine concentration are depicted by the dark gray and white boxes, respectively. Variant rs4778636 is located within IL16. The asterisk indicates undetectable concentration of circulating IL-16. The A allele of rs4778636 leads to nonsense-mediated decay of IL16 mRNA and thus circulating concentration of IL-16 is undetectable in rs4778636-AA homozygotes. The box indicates the 25th and 75th percentile. The black horizontal lines within the boxes represent median. The whiskers indicate the least and the maximum value excluding outliers, indicated by dots.