Table 2.
The pathways activated in both nrf2a-overexpressing embryos and DEM/tBHQ-treated larvae.
| p value | Pathway name | Genes |
|---|---|---|
| 3.33E − 9 | Glutathione conjugation | gclc, gsto2, gstp1, gclm, gsta.1 |
| 4.13E − 7 | Phase II conjugation | gclc, gsto2, gstp1, ugdh, gclm, gsta.1 |
| 7.44E − 7 | Detoxification of reactive oxygen species | txn, gstp1, prdx1, gsr |
| 8.26E − 7 | Biological oxidations | gclc, gstp1, gsto2, aoc2, ugdh, gclm, gsta.1 |
| 1.39E − 3 | Vitamin C (ascorbate) metabolism | gsto2 |
| 1.78E − 3 | Sulfur amino acid metabolism | gclc, sqrdl, gclm |
| 4.77E − 3 | TP53 regulates metabolic genes | txn, prdx1, gsr |
| 6.76E − 3 | Glutathione synthesis and recycling | gclc, gclm |
| 8.46E − 3 | Cellular responses to stress | txn, gstp1, prdx1, gsr |
| 8.83E − 3 | Metabolism | gclc, pck1, gstp1, sqrdl, txn, gsta.1, gsr, pcxb, gsto2, aoc2, pgd, ugdh, gclm |
Bold genes encode enzymes related to the glucose metabolism process.