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. 2016 Dec 22;100(1):51–63. doi: 10.1016/j.ajhg.2016.11.016

Figure 2.

Figure 2

rs2979489 Is Localized to a Potential Regulatory Site that Involves Transition Binding of GATA2 to GATA1 during Erythrocyte Differentiation

Top shows gene-track view of rs2979489 location in the RBPMS/GTF2E2 gene region. Bottom left: gene track of RBPMS gene showing overlap of GATA2, GATA1, and ATAC-seq peaks (red, blue, and green, respectively) during human erythroid differentiation. Bottom right: overlap of ATAC-seq (green) and H3K27ac ChIP-seq (black) during differentiation at the region proximal to the SNP rs2979489. The gray horizontal line indicates the position of SNP rs 2979489. D0, day 0; H6, hour 6; D3, day 3; D4, day 4; and D5, day 5 of erythroid differentiation time-course post-induction of differentiation.