Table 1.
Findings from the METAL and MANTRA Trans-ethnic Analyses
| Trait | SNP | Chr | Gene | c/nc | N |
METAL |
MANTRA |
RE2 |
||
|---|---|---|---|---|---|---|---|---|---|---|
| Effect (SE) | p | Log10BF | posthg | p | ||||||
| Hb | rs2299433 | 7 | MET | T/C | 63,091 | 0.041 (0.008) | 6.16 × 10−8 | 6.195 | 0.027 | 1.20 × 10−7 |
| Hct | rs6430549 | 2 | TMEM163 / ACMSD | A/G | 71,647 | 0.103 (0.018) | 4.96 × 10−9 | 7.408 | 0.120 | 8.46 × 10−9 |
| Hct | rs2299433 | 7 | MET | T/C | 63,532 | 0.102 (0.019) | 5.66 × 10−8 | 6.199 | 0.099 | 9.87 × 10−8 |
| MCH | rs2060597 | 3 | PLCL2 | T/C | 38,836 | 0.006 (0.001) | 4.18 × 10−10 | 8.178 | 0.009 | 9.75 × 10−10 |
| MCH | rs2979489 | 8 | RBPMS | A/G | 37,531 | −0.002 (0.001) | 8.89 × 10−5 | 9.723 | 1.000 | 1.19 × 10−12 |
| MCV | rs10929547 | 2 | ID2 | A/C | 50,870 | −0.002 (0.0003) | 2.50 × 10−9 | 7.977 | 0.007 | 2.14 × 10−9 |
| MCV | rs9821630 | 3 | PLCL2 | A/G | 48,697 | −0.002 (0.0004) | 6.86 × 10−9 | 7.864 | 0.004 | 2.44 × 10−9 |
| MCV | rs2979489 | 8 | RBPMS | A/G | 48,697 | −0.002 (0.0004) | 7.24 × 10−9 | 7.961 | 0.003 | 1.65 × 10−9 |
| MCV | rs6121246 | 20 | FOXS1 | T/C | 49,896 | 0.003 (0.001) | 4.05 × 10−7 | 6.296 | 0.003 | 8.31 × 10−8 |
Abbreviations are as follows: chr, chromosome number; c/nc, coding/non-coding allele; n, number of participants; SE, standard error; p, p value; log10BF, logarithm of Bayes Factor; posthg, posterior probability of heterogeneity.