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. 2016 Jan 6;41(1):52–59. doi: 10.1016/j.jgr.2015.12.011

Fig. 4.

Fig. 4

The effect of rosiglitazone combined with Korean red ginseng on adipose tissue morphology and crown-like structures (CLSs) in diet-induced obese mice. (A) Representative figures of epididymal fat after 4 days of treatment (red arrows indicate CLSs of macrophages. (B) Comparison of CLSs per field. (C) Ccl2 gene expression in adipose tissue. (D) Arg1 gene expression in adipose tissue. (E) Comparison of the mean surface area of adipocytes. (F) The distribution of adipocyte size. Data are presented as the mean ± the standard error of the mean. * p < 0.05. Ccl2 (MCP-1), chemokine (C–C motif) ligand 2; CON, study group treated with 0.5% methyl cellulose and 0.9% saline; KRG, study group treated with 500 mg/kg b.w. of Korean Red Ginseng; RK, study group treated with 500 mg/kg b.w. KRG combined with 3.75 mg/kg b.w. rosiglitazone; ROSI, study group treated with 3.75 mg/kg b.w. of rosiglitazone.